Bases Moleculares da Regulação Gênica

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Profa. Angela K. Cruz

Aula

Artigos de revisão - 22/03:

Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation. Goodrich JA, Tjian R. Nat Rev Genet. 2010 Aug;11(8):549-58.

Combinatorial control of gene expression - Reményi A, Scholer HR, Wilmanns M. Nature Structural & Molecular Biology, 2004 Sept11(9): 812-815


Artigo seminal - 29/03: Aline Cutrim Dragalzew

Mechanism of initiation and repression of in vitro transcription of the lac operon of Escherichia coli.Eron L, Block R. Proc Natl Acad Sci U S A. 1971 Aug;68(8):1828-32.

 

Artigo contemporâneo - 29/03 : Rui MP Junior

Tiny RNAs associated with transcription start sites in animals. Taft RJ, Glazov EA, Cloonan N, Simons C, Stephen S, Faulkner GJ, Lassmann T, Forrest AR, Grimmond SM, Schroder K, Irvine K, Arakawa T, Nakamura M, Kubosaki A, Hayashida K, Kawazu C, Murata M, Nishiyori H, Fukuda S, Kawai J, Daub CO, Hume DA, Suzuki H, Orlando V, Carninci P, Hayashizaki Y, Mattick JS. Nat Genet. 2009 May;41(5):572-8. Epub 2009 Apr 19.

 

SUGESTÕES DE LEITURA

Determining the specificity of protein-DNA interactionsStormo GD, Zhao Y. Nat Rev Genet. 2010 Nov;11(11):751-60.

Structure and mechanism of the RNA polymerase II transcription machinery. Hahn S. Nat Struct Mol Biol. 2004 May;11(5):394-403.

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Taft RJ, Simons C, Nahkuri S, Oey H, Korbie DJ, Mercer TR, Holst J, Ritchie W, Wong JJ, Rasko JE, Rokhsar DS, Degnan BM, Mattick JS. Nat Struct Mol Biol. 2010 Aug;17(8):1030-4. Epub 2010 Jul 11.

Last Updated on Monday, 21 May 2012 16:20