Bases Moleculares da Regulação Gênica

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Regulação pós-transcricional e pós-traducional

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Profa Tie Koide

 

Artigos seminais (24/05): Relber Gonçalves

Sensing small molecules by nascent RNA: a mechanism to control transcription in bacteria. A.S. Mironov, I. Gusarov, R. Rafikov, L.E. Lopez, K. Shatalin, R.A. Kreneva, D.A. Perumov and E. Nudler, Cell, 111 (2002), pp. 747756

 

Artigos contemporaneos (24/05): Mayra D. Macedo

Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch. G. Perdrizet, I. Artsimovitch, R. Furman, T. Sosnick & T. Pan. PNAS, 109 -(2012), pp 3323-3328

 

Sugestões de leitura

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF). Lau AG, Irier HA, Gu J, Tian D, Ku L, Liu G, Xia M, Fritsch B, Zheng JQ, Dingledine R, Xu B, Lu B, Feng Y. (2010). Proc Natl Acad Sci U S A; 107(36):15945-50.

An allosteric self-splicing ribozyme triggered by a bacterial second messenger. Lee et al., 2010 E.R. Lee, J.L. Baker, Z. Weinberg, N. Sudarsan and R.R. Breaker, Science, 329 (2010)

Gene regulation by riboswitches. Mandal M, Breaker RR. (2004). Nat Rev Mol Cell Biol.; 5(6):451-63.

Prospects for Riboswitch Discovery and Analysis. Breaker, Molecular Cell Volume 43, Issue 6(2011).

Molecular Mechanisms of Long Noncoding RNAs. Wang & Chang. Molecular Cell Volume 43, Issue 6(2011).


Last Updated on Monday, 30 April 2012 16:43